1613437-66-3
1613437-66-3 structure
- Name: KBP-7018
- Chemical Name: KBP-7018
- CAS Number: 1613437-66-3
- Molecular Formula: C31H30N4O5
- Molecular Weight: 538.604
- Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK c-Kit
- Create Date: 2020-01-12 09:48:50
- Modify Date: 2024-09-18 10:59:36
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A novel potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively; also potently inhibits FLT3, VEGFR2, Fyn, PDGFRα and VEGFR2; shows promising outcomes for the treatments of idiopathic pulmonary fibrosis (IPF).
| Name | KBP-7018 |
|---|
| Description | A novel potent, multikinase inhibitor with IC50 of 10, 7.6 and 25 nM for c-Kit, RET and PDGFRβ, respectively; also potently inhibits FLT3, VEGFR2, Fyn, PDGFRα and VEGFR2; shows promising outcomes for the treatments of idiopathic pulmonary fibrosis (IPF). |
|---|---|
| References | References 1. Huang Z, et al. ACS Med Chem Lett. 2017 Sep 30;8(11):1142-1147. 2. Huang Z, et al. Drug Des Devel Ther. 2015 Aug 5;9:4319-28. View Related Products by Target c-Kit |
| Molecular Formula | C31H30N4O5 |
|---|---|
| Molecular Weight | 538.604 |