UNC0379 trifluoroacetate salt
Modify Date: 2024-01-02 17:52:58
UNC0379 trifluoroacetate salt structure
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Common Name | UNC0379 trifluoroacetate salt | ||
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| CAS Number | 1620401-83-3 | Molecular Weight | 527.580 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H36F3N5O4 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of UNC0379 trifluoroacetate saltUNC0379 trifluoroacetate is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8 with IC50 of 7.3±1.0 uM; selective over 15 other methyltransferases.IC50 value: 7.3±1.0 uMTarget: SETD8 inhibitorUNC0379 is a synthetic small-molecule inhibitor that displays inhibitory activity in multiple biochemical assays and is selective for SETD8 over 15 other methyltransferases. The binding affinity of UNC0379 to SETD8 was determined using biophysical assays such as ITC (isothermal titration calorimetry) and SPR (surface plasmon resonance) and is largely consistent with its potency in biochemical assays. |
| Name | UNC0379 trifluoroacetate |
|---|---|
| Synonym | More Synonyms |
| Description | UNC0379 trifluoroacetate is a selective, substrate-competitive inhibitor of the lysine methyltransferase SETD8 with IC50 of 7.3±1.0 uM; selective over 15 other methyltransferases.IC50 value: 7.3±1.0 uMTarget: SETD8 inhibitorUNC0379 is a synthetic small-molecule inhibitor that displays inhibitory activity in multiple biochemical assays and is selective for SETD8 over 15 other methyltransferases. The binding affinity of UNC0379 to SETD8 was determined using biophysical assays such as ITC (isothermal titration calorimetry) and SPR (surface plasmon resonance) and is largely consistent with its potency in biochemical assays. |
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| Related Catalog | |
| References |
| Molecular Formula | C25H36F3N5O4 |
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| Molecular Weight | 527.580 |
| Exact Mass | 527.271912 |
| Storage condition | 2-8℃ |
| RIDADR | NONH for all modes of transport |
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| 6,7-Dimethoxy-2-(1-pyrrolidinyl)-N-[5-(1-pyrrolidinyl)pentyl]-4-quinazolinamine trifluoroacetate (1:1) |
| Acetic acid, 2,2,2-trifluoro-, compd. with 6,7-dimethoxy-2-(1-pyrrolidinyl)-N-[5-(1-pyrrolidinyl)pentyl]-4-quinazolinamine (1:1) |
| UNC0379 (trifluoroacetate) |