AP5 sodium

Modify Date: 2024-01-18 21:59:01

AP5 sodium Structure
AP5 sodium structure
Common Name AP5 sodium
CAS Number 1623143-67-8 Molecular Weight 483.51
Density N/A Boiling Point N/A
Molecular Formula C28H27FNNaO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AP5 sodium


AP5 sodium is a potent, orall active, and selective GPR40 receptor agonist with a positive allosteric modulation of endogenous ligand (AgoPAM). AP5 sodium demonstrates rat and human inositol monophosphate (IP1) EC50 values of 0.49 nM and 0.8 nM against the GPR40 receptor, respectively. AP5 sodium has the potential for type II diabetes research[1].

 Names

Name AP5 sodium

 AP5 sodium Biological Activity

Description AP5 sodium is a potent, orall active, and selective GPR40 receptor agonist with a positive allosteric modulation of endogenous ligand (AgoPAM). AP5 sodium demonstrates rat and human inositol monophosphate (IP1) EC50 values of 0.49 nM and 0.8 nM against the GPR40 receptor, respectively. AP5 sodium has the potential for type II diabetes research[1].
Related Catalog
References

[1]. Chen HY, et al. Structure-Activity Relationship of Novel and Selective Biaryl-Chroman GPR40 AgoPAMs. ACS Med Chem Lett. 2018 Jun 14;9(7):685-690.

 Chemical & Physical Properties

Molecular Formula C28H27FNNaO4
Molecular Weight 483.51
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