Gü2602

Modify Date: 2024-01-09 18:52:49

Gü2602 Structure
Gü2602 structure
Common Name Gü2602
CAS Number 1627094-88-5 Molecular Weight 318.37
Density N/A Boiling Point N/A
Molecular Formula C16H22N4O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Gü2602


Gü2602 is a potent, reversible cathepsin K (CatK) inhibitor with a Ki of 0.013 nM for mature CatK (mCatK). Gü2602 suppresses the autocatalytic activation of the cathepsin K zymogen[1].

 Names

Name Gü2602

 Gü2602 Biological Activity

Description Gü2602 is a potent, reversible cathepsin K (CatK) inhibitor with a Ki of 0.013 nM for mature CatK (mCatK). Gü2602 suppresses the autocatalytic activation of the cathepsin K zymogen[1].
Related Catalog
Target

Ki: 0.013 nM (mCatK)[1]

References

[1]. Benýšek J, et al. Highly potent inhibitors of cathepsin K with a differently positioned cyanohydrazide warhead: structural analysis of binding mode to mature and zymogen-like enzymes. J Enzyme Inhib Med Chem. 2022 Dec;37(1):515-526.

 Chemical & Physical Properties

Molecular Formula C16H22N4O3
Molecular Weight 318.37