TAK-020

Modify Date: 2024-01-11 23:08:16

Use of TAK-020

TAK-020 is a covalent Btk inhibitor, which becomes the clinical candidate.

Name	TAK-020

Description	TAK-020 is a covalent Btk inhibitor, which becomes the clinical candidate.
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk
References	[1]. Sabat M, et al. Discovery of the Bruton's Tyrosine Kinase Inhibitor Clinical Candidate TAK-020 (S)-5-(1-((1-Acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one, by Fragment-Based Drug Design. J Med Chem. 2021 Sep 9;64(17):12893-12902.

Molecular Formula	C₁₈H₁₇N₅O₃
Molecular Weight	351.36

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