(S)-PFI 2 hydrochloride
Modify Date: 2024-01-02 19:37:31
(S)-PFI 2 hydrochloride structure
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Common Name | (S)-PFI 2 hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 1627607-88-8 | Molecular Weight | 535.982 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H26ClF4N3O3S | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of (S)-PFI 2 hydrochlorideNegative control of (R)-PFI 2 hydrochloride. Exhibits 500-fold lower activity in a SETD7 enzymatic assay (IC50 = 1 μM) compared to the active enantiomer. |
| Name | 8-Fluoro-N-{(2S)-1-oxo-1-(1-pyrrolidinyl)-3-[3-(trifluoromethyl)phenyl]-2-propanyl}-1,2,3,4-tetrahydro-6-isoquinolinesulfonamide hydrochloride (1:1) |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C23H26ClF4N3O3S |
|---|---|
| Molecular Weight | 535.982 |
| Exact Mass | 535.131958 |
| RIDADR | NONH for all modes of transport |
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(R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells.
Proc. Natl. Acad. Sci. U. S. A. 111(35) , 12853-8, (2014) SET domain containing (lysine methyltransferase) 7 (SETD7) is implicated in multiple signaling and disease related pathways with a broad diversity of reported substrates. Here, we report the discovery... |
| 8-Fluoro-N-{(2S)-1-oxo-1-(1-pyrrolidinyl)-3-[3-(trifluoromethyl)phenyl]-2-propanyl}-1,2,3,4-tetrahydro-6-isoquinolinesulfonamide hydrochloride (1:1) |
| 6-Isoquinolinesulfonamide, 8-fluoro-1,2,3,4-tetrahydro-N-[(1S)-2-oxo-2-(1-pyrrolidinyl)-1-[[3-(trifluoromethyl)phenyl]methyl]ethyl]-, hydrochloride (1:1) |
| (S)-PFI-2 HCl |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: (S)-PFI-2 HCl
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: (S)-PFI-2 HCl
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: (S)-PFI-2 HCl
- Price: $390.0/5mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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