NSC756093

Modify Date: 2024-01-07 21:44:03

NSC756093 Structure
NSC756093 structure
Common Name NSC756093
CAS Number 1629908-92-4 Molecular Weight 337.37
Density 1.4±0.1 g/cm3 Boiling Point 561.8±50.0 °C at 760 mmHg
Molecular Formula C20H19NO4 Melting Point N/A
MSDS Chinese USA Flash Point 293.6±30.1 °C
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning

 Use of NSC756093


NSC756093 is a potent inhibitor of the GBP1:PIM1 interaction. NSC756093 can potentially revert resistance to paclitaxel. NSC756093 can be used for ovarian cancer research[1].

 Names

Name 4-(2-Hydroxyethyl)-6-methoxy-9-phenyl-4,9-dihydrofuro[3,4-b]quinolin-1(3H)-one
Synonym More Synonyms

 NSC756093 Biological Activity

Description NSC756093 is a potent inhibitor of the GBP1:PIM1 interaction. NSC756093 can potentially revert resistance to paclitaxel. NSC756093 can be used for ovarian cancer research[1].
Related Catalog
References

[1]. Andreoli M, et al. Identification of the first inhibitor of the GBP1:PIM1 interaction. Implications for the development of a new class of anticancer agents against paclitaxel resistant cancer cells. J Med Chem. 2014 Oct 9;57(19):7916-32.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 561.8±50.0 °C at 760 mmHg
Molecular Formula C20H19NO4
Molecular Weight 337.37
Flash Point 293.6±30.1 °C
Exact Mass 337.131409
LogP 1.48
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.668
Storage condition -20°C

 Safety Information

Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H302-H400
Precautionary Statements P273-P301 + P312 + P330-P391
RIDADR UN 3077 9 / PGIII

 Synonyms

Furo[3,4-b]quinolin-1(3H)-one, 4,9-dihydro-4-(2-hydroxyethyl)-6-methoxy-9-phenyl-
4-(2-Hydroxyethyl)-6-methoxy-9-phenyl-4,9-dihydrofuro[3,4-b]quinolin-1(3H)-one