PNR-7-02
Modify Date: 2023-01-11 17:02:03
PNR-7-02 structure
|
Common Name | PNR-7-02 | ||
|---|---|---|---|---|
| CAS Number | 1633660-76-0 | Molecular Weight | 445.921 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H16ClN3O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PNR-7-02PNR-7-02 is a specific inhibitor of human DNA Polymerase η (hPol η) with IC50 of 8 uM, exhibits 5-10-fold specificity for hPol η over other replicative Pols; binds to a site on the little finger domain and interferes with the proper orientation of template DNA to inhibit hpol η; potentiates the effects of cisplatin in tumor cells accompanied with increased γH2AX formation. |
| Name | PNR-7-02 |
|---|
| Description | PNR-7-02 is a specific inhibitor of human DNA Polymerase η (hPol η) with IC50 of 8 uM, exhibits 5-10-fold specificity for hPol η over other replicative Pols; binds to a site on the little finger domain and interferes with the proper orientation of template DNA to inhibit hpol η; potentiates the effects of cisplatin in tumor cells accompanied with increased γH2AX formation. |
|---|---|
| References | References 1. Zafar MK, et al. Biochemistry. 2018 Feb 20;57(7):1262-1273. View Related Products by Target DNA/RNA Synthesis |
| Molecular Formula | C24H16ClN3O2S |
|---|---|
| Molecular Weight | 445.921 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: PNR-7-02
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: PNR-7-02
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: PNR-7-02
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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