(2H24)Undecane

Modify Date: 2024-01-05 17:38:08

(2H24)Undecane Structure
(2H24)Undecane structure
Common Name (2H24)Undecane
CAS Number 164858-54-2 Molecular Weight 180.456
Density 0.7±0.1 g/cm3 Boiling Point 196.3±3.0 °C at 760 mmHg
Molecular Formula C11D24 Melting Point N/A
MSDS USA Flash Point 60.0±0.0 °C
Symbol GHS08
GHS08
Signal Word Danger

 Use of (2H24)Undecane


Undecane-d24 is the deuterium labeled Undecane[1]. Undecane has anti-allergic and anti-inflammatory activities on sensitized rat basophilic leukemia (RBL-2H3) mast cells and HaCaT keratinocytes. In sensitized mast cells, Undecane inhibits degranulation and the secretion of histamine and TNF-α[2].

 Names

Name n-undecane-d24
Synonym More Synonyms

 (2H24)Undecane Biological Activity

Description Undecane-d24 is the deuterium labeled Undecane[1]. Undecane has anti-allergic and anti-inflammatory activities on sensitized rat basophilic leukemia (RBL-2H3) mast cells and HaCaT keratinocytes. In sensitized mast cells, Undecane inhibits degranulation and the secretion of histamine and TNF-α[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Choi D, Kang W, Park T. Anti-Allergic and Anti-Inflammatory Effects of Undecane on Mast Cells and Keratinocytes. Molecules. 2020;25(7):1554. Published 2020 Mar 28.  

 Chemical & Physical Properties

Density 0.7±0.1 g/cm3
Boiling Point 196.3±3.0 °C at 760 mmHg
Molecular Formula C11D24
Molecular Weight 180.456
Flash Point 60.0±0.0 °C
Exact Mass 180.338440
LogP 6.60
Vapour Pressure 0.6±0.2 mmHg at 25°C
Index of Refraction 1.419

 Safety Information

Symbol GHS08
GHS08
Signal Word Danger
Hazard Statements H304
Supplemental HS Repeated exposure may cause skin dryness or cracking.
Precautionary Statements P301 + P310-P331
RIDADR UN 2330 3 / PGIII

 Synonyms

(H)Undecane
Undecane-d