164858-54-2

164858-54-2 structure
164858-54-2 structure
  • Name: (2H24)Undecane
  • Chemical Name: n-undecane-d24
  • CAS Number: 164858-54-2
  • Molecular Formula: C11D24
  • Molecular Weight: 180.456
  • Catalog: Research Areas Infection
  • Create Date: 2018-07-14 12:01:25
  • Modify Date: 2024-01-05 17:38:08
  • Undecane-d24 is the deuterium labeled Undecane[1]. Undecane has anti-allergic and anti-inflammatory activities on sensitized rat basophilic leukemia (RBL-2H3) mast cells and HaCaT keratinocytes. In sensitized mast cells, Undecane inhibits degranulation and the secretion of histamine and TNF-α[2].

Name n-undecane-d24
Synonyms (H)Undecane
Undecane-d
Description Undecane-d24 is the deuterium labeled Undecane[1]. Undecane has anti-allergic and anti-inflammatory activities on sensitized rat basophilic leukemia (RBL-2H3) mast cells and HaCaT keratinocytes. In sensitized mast cells, Undecane inhibits degranulation and the secretion of histamine and TNF-α[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Choi D, Kang W, Park T. Anti-Allergic and Anti-Inflammatory Effects of Undecane on Mast Cells and Keratinocytes. Molecules. 2020;25(7):1554. Published 2020 Mar 28.  

Density 0.7±0.1 g/cm3
Boiling Point 196.3±3.0 °C at 760 mmHg
Molecular Formula C11D24
Molecular Weight 180.456
Flash Point 60.0±0.0 °C
Exact Mass 180.338440
LogP 6.60
Vapour Pressure 0.6±0.2 mmHg at 25°C
Index of Refraction 1.419
Symbol GHS08
GHS08
Signal Word Danger
Hazard Statements H304
Supplemental HS Repeated exposure may cause skin dryness or cracking.
Precautionary Statements P301 + P310-P331
RIDADR UN 2330 3 / PGIII