ML352

Modify Date: 2024-01-14 17:09:06

ML352 Structure
ML352 structure
Common Name ML352
CAS Number 1649450-12-3 Molecular Weight 387.473
Density 1.1±0.1 g/cm3 Boiling Point 538.1±50.0 °C at 760 mmHg
Molecular Formula C21H29N3O4 Melting Point N/A
MSDS N/A Flash Point 279.2±30.1 °C

 Use of ML352


ML352 is a noncompetitive inhibitor of the presynaptic choline transporter (CHT) with Kivalues of 92 and 166 nM for HEK293 cells expressing human CHT and mouse forebrain synaptosomes, respectively[1].

 Names

Name N-[(3-Isopropyl-1,2-oxazol-5-yl)methyl]-4-methoxy-3-[(1-methyl-4-piperidinyl)oxy]benzamide
Synonym More Synonyms

 ML352 Biological Activity

Description ML352 is a noncompetitive inhibitor of the presynaptic choline transporter (CHT) with Kivalues of 92 and 166 nM for HEK293 cells expressing human CHT and mouse forebrain synaptosomes, respectively[1].
Related Catalog
References

[1]. Ennis EA, Wright J, Retzlaff CL, McManus OB, Lin Z, Huang X, et al. Identification and characterization of ML352: a novel, noncompetitive inhibitor of the presynaptic choline transporter. ACS Chem Neurosci. 2015 Mar 18;6(3):417-27.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 538.1±50.0 °C at 760 mmHg
Molecular Formula C21H29N3O4
Molecular Weight 387.473
Flash Point 279.2±30.1 °C
Exact Mass 387.215820
LogP 2.23
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.546

 Synonyms

N-[(3-Isopropyl-1,2-oxazol-5-yl)methyl]-4-methoxy-3-[(1-methyl-4-piperidinyl)oxy]benzamide
MFCD28975158
Benzamide, 4-methoxy-N-[[3-(1-methylethyl)-5-isoxazolyl]methyl]-3-[(1-methyl-4-piperidinyl)oxy]-
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