Neotame

Modify Date: 2024-01-02 22:11:03

Neotame Structure
Neotame structure
Common Name Neotame
CAS Number 165450-17-9 Molecular Weight 378.463
Density 1.1±0.1 g/cm3 Boiling Point 535.8±60.0 °C at 760 mmHg
Molecular Formula C20H30N2O5 Melting Point 80.9-83.4ºC
MSDS Chinese USA Flash Point 277.9±32.9 °C

 Use of Neotame


Neotame is a derivative of Aspartame and is a low-caloric and high-intensity artificial sweetener that is 7000-13,000 times sweeter than sugar. Neotame is a non-nutritive sweetener and flavor enhancer that can be used in a variety of foods[1][2].

 Names

Name neotame
Synonym More Synonyms

 Neotame Biological Activity

Description Neotame is a derivative of Aspartame and is a low-caloric and high-intensity artificial sweetener that is 7000-13,000 times sweeter than sugar. Neotame is a non-nutritive sweetener and flavor enhancer that can be used in a variety of foods[1][2].
Related Catalog
References

[1]. Liang Chi, et al. Effects of the Artificial Sweetener Neotame on the Gut Microbiome and Fecal Metabolites in Mice. Molecules. 2018 Feb 9;23(2):367.

[2]. Anuradha Kumari, et al. Stability of Aspartame and Neotame in Pasteurized and In-Bottle Sterilized Flavoured Milk. Food Chem. 2016 Apr 1;196:533-8.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 535.8±60.0 °C at 760 mmHg
Melting Point 80.9-83.4ºC
Molecular Formula C20H30N2O5
Molecular Weight 378.463
Flash Point 277.9±32.9 °C
Exact Mass 378.215485
PSA 104.73000
LogP 4.73
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.530

 Safety Information

Safety Phrases 24/25
RIDADR NONH for all modes of transport
HS Code 2924299090

 Synthetic Route

~87%

Neotame Structure

Neotame

CAS#:165450-17-9

Literature: Ajinomoto Co., Inc. Patent: US6914151 B1, 2005 ; Location in patent: Page/Page column 5-6 ;

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Methyl N-(3,3-dimethylbutyl)-L-α-aspartyl-L-phenylalaninate
UNII-VJ597D52EX
(3S)-3-(3,3-dimethylbutylamino)-4-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]amino]-4-oxobutanoic acid
(3S,4E)-3-[(3,3-Dimethylbutyl)amino]-4-hydroxy-4-{[(2S)-1-methoxy-1-oxo-3-phenyl-2-propanyl]imino}butanoic acid
L-Phenylalanine, N-[(2S)-3-carboxy-2-[(3,3-dimethylbutyl)amino]-1-hydroxypropylidene]-, methyl ester, (E)-
Neotame
Methyl N-(3,3-dimethylbutyl)-L-α-aspartylphenylalaninate
E961
L-phenylalanine, N-(3,3-dimethylbutyl)-L-α-aspartyl-, methyl ester
N-(3,3-Dimethylbutyl)-L-a-aspartyl-L-phenylalanine Methyl Ester
VJ597D52EX
N-(3,3-dimethylbutyl)-L-aspartyl-L-phenylalanine methyl ester
Phenylalanine, N-(3,3-dimethylbutyl)-L-α-aspartyl-, methyl ester
(S)-3-((3,3-Dimethylbutyl)amino)-4-(((S)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amino)-4-oxobutanoic ac
N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine methyl ester
(S)-3-((3,3-Dimethylbutyl)amino)-4-(((S)-1-methoxy-1-oxo-3-phenylpropan-2-yl)amino)-4-oxobutanoic acid
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Price: ¥36.3/5g

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