PNU 96415E

Modify Date: 2024-04-03 20:57:00

PNU 96415E Structure
PNU 96415E structure
Common Name PNU 96415E
CAS Number 170856-41-4 Molecular Weight 413.35600
Density N/A Boiling Point N/A
Molecular Formula C21H27Cl2FN2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PNU 96415E


PNU-96415E is a selective D4/5-HT2A antagonist. PNU-96415E may have potential antipsychotic efficacy[1].

 Names

Name 1-[2-(3,4-dihydro-1H-isochromen-1-yl)ethyl]-4-(4-fluorophenyl)piperazine,dihydrochloride

 PNU 96415E Biological Activity

Description PNU-96415E is a selective D4/5-HT2A antagonist. PNU-96415E may have potential antipsychotic efficacy[1].
Related Catalog
Target

D4 Receptor

5-HT2A Receptor

In Vivo PNU-96415E blockes 5-HTP-induced bead twitches in mice and stereotypic behaviours produced by high doses of amphetamine and methylphenidate[1].
References

[1]. Kulkarni SK, et al. Dopamine D4 receptors and development of newer antipsychotic drugs. Fundam Clin Pharmacol. 2000;14(6):529-539.

 Chemical & Physical Properties

Molecular Formula C21H27Cl2FN2O
Molecular Weight 413.35600
Exact Mass 412.14800
PSA 15.71000
LogP 5.25870
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