Sonepiprazole
Modify Date: 2024-01-05 23:04:44
Sonepiprazole structure
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Common Name | Sonepiprazole | ||
|---|---|---|---|---|
| CAS Number | 170858-33-0 | Molecular Weight | 401.52200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H27N3O3S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of SonepiprazoleSonepiprazole (PNU-101387G) is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively[1]. |
| Name | Sonepiprazole hydrate |
|---|---|
| Synonym | More Synonyms |
| Description | Sonepiprazole (PNU-101387G) is a selective D4 dopamine antagonist with Kis of 3.6, 10.1, 5147, and 7430 nM for rD4-Dopamine, hD4.2-Dopamine, rD2-Dopamine, and Histamine-H1 receptors, respectively[1]. |
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| Related Catalog | |
| Target |
rD4 Receptor:3.6 nM (Ki) hD4 Receptor:10.1 nM (Ki) rD2 Receptor:5147 nM (Ki) Histamine H1 Receptor:7430 nM (Ki) |
| In Vitro | Sonepiprazole exhibits highly specific binding to the D4 dopamine receptor with more than 100-fold selectivity for the D4 receptor over other receptors, including dopamine, serotonin, and adrenergic receptors[1]. |
| References |
| Molecular Formula | C21H27N3O3S |
|---|---|
| Molecular Weight | 401.52200 |
| Exact Mass | 401.17700 |
| PSA | 84.25000 |
| LogP | 3.94410 |
| Vapour Pressure | 5.27E-15mmHg at 25°C |
| Sonepiprazole |
| Ritanserin |
| Benzenesulfonamide |