Frunevetmab
Modify Date: 2024-01-06 17:23:01
Frunevetmab structure
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Common Name | Frunevetmab | ||
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| CAS Number | 1708936-80-4 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | N/A | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of FrunevetmabFrunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a Kd of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats[1][2]. |
| Name | Frunevetmab |
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| Description | Frunevetmab (NV-02) is a felinized anti-nerve growth factor (NGF) monoclonal antibody with a Kd of 20 pM. Frunevetmab can effectively decrease osteoarthritis (OA) pain in cats[1][2]. |
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| Related Catalog | |
| Target |
Kd: 20 pM (NGF)[2] |
| In Vitro | Frunevetmab (NV-02) neutralizes NGF with high affinity and potency and does not bind complement[2]. |
| In Vivo | Frunevetmab (1.0-2.8 mg/kg; s.c; on days 0, 28, and 56) shows positive treatment effects in cats with naturally-occurring OA pain and associated mobility impairment and disability[1]. Animal Model: Cats with naturally-occurring OA pain and associated mobility impairment and disability[1] Dosage: 1.0-2.8 mg/kg Administration: s.c; 3 times at 28-day intervals; on days 0, 28, and 56 Result: Reliefed the pain from osteoarthritis in cats. |
| References |
| No Any Chemical & Physical Properties |