12-epi-TadalafilTadalafil structure
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Common Name | 12-epi-TadalafilTadalafil | ||
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CAS Number | 171596-27-3 | Molecular Weight | 389.40 | |
Density | 1.51±0.1 g/cm3 (20 ºC 760 Torr) | Boiling Point | N/A | |
Molecular Formula | C22H19N3O4 | Melting Point | 295-296 ºC | |
MSDS | N/A | Flash Point | N/A |
Use of 12-epi-TadalafilTadalafilcis-Tadalafil is a PDE5 inhibitor (IC50: 0.09 μM). cis-Tadalafil can be used for research of cardiovascular diseases[1]. |
Name | (6R,12aS)-2,3,6,7,12,12a-hexahydro-2-methyl-6-(3,4-methylenedioxyphenyl)-pyrazino[2',1':6,1]pyrido[3,4-b]indole-1,4-dione |
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Synonym | More Synonyms |
Description | cis-Tadalafil is a PDE5 inhibitor (IC50: 0.09 μM). cis-Tadalafil can be used for research of cardiovascular diseases[1]. |
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Related Catalog | |
Target |
PDE5:0.09 μM (IC50) |
In Vitro | cis-Tadalafil (Compound 12b) 抑制 PDE5,IC50 为 0.09 μM[1]。 |
References |
Density | 1.51±0.1 g/cm3 (20 ºC 760 Torr) |
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Melting Point | 295-296 ºC |
Molecular Formula | C22H19N3O4 |
Molecular Weight | 389.40 |
Exact Mass | 389.13800 |
PSA | 74.87000 |
LogP | 2.08710 |
Water Solubility | Insuluble (8.6E-3 g/L) (25 ºC) |
~95% 12-epi-Tadalafi... CAS#:171596-27-3 |
Literature: Tetrahedron Asymmetry, , vol. 19, # 4 p. 435 - 442 |
~81% 12-epi-Tadalafi... CAS#:171596-27-3 |
Literature: Journal of Medicinal Chemistry, , vol. 46, # 21 p. 4533 - 4542 |
~1% 12-epi-Tadalafi... CAS#:171596-27-3 |
Literature: Bioorganic and Medicinal Chemistry, , vol. 12, # 6 p. 1505 - 1515 |
~% 12-epi-Tadalafi... CAS#:171596-27-3 |
Literature: Journal of Medicinal Chemistry, , vol. 46, # 21 p. 4533 - 4542 |
~% 12-epi-Tadalafi... CAS#:171596-27-3 |
Literature: Journal of Medicinal Chemistry, , vol. 46, # 21 p. 4533 - 4542 |
~% 12-epi-Tadalafi... CAS#:171596-27-3 |
Literature: Journal of Medicinal Chemistry, , vol. 46, # 21 p. 4533 - 4542 |
~% 12-epi-Tadalafi... CAS#:171596-27-3 |
Literature: Bioorganic and Medicinal Chemistry, , vol. 12, # 6 p. 1505 - 1515 |
~% 12-epi-Tadalafi... CAS#:171596-27-3 |
Literature: Bioorganic and Medicinal Chemistry, , vol. 12, # 6 p. 1505 - 1515 |
UNII-E319TQ0B6R |
cis-ent-Tadalafil |
PYR403 |
12-epi-TadalafilTadalafil |
Tadalafil Impurity 13 |