N-Boc-trans-4-N-Fmoc-amino-L-proline

Modify Date: 2024-01-03 16:16:48

N-Boc-trans-4-N-Fmoc-amino-L-proline Structure
N-Boc-trans-4-N-Fmoc-amino-L-proline structure
Common Name N-Boc-trans-4-N-Fmoc-amino-L-proline
CAS Number 176486-63-8 Molecular Weight 452.500
Density 1.3±0.1 g/cm3 Boiling Point 650.2±55.0 °C at 760 mmHg
Molecular Formula C25H28N2O6 Melting Point 199ºC(lit.)
MSDS USA Flash Point 347.0±31.5 °C

 Use of N-Boc-trans-4-N-Fmoc-amino-L-proline


(2S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid is a proline derivative[1].

 Names

Name (2S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid
Synonym More Synonyms

 N-Boc-trans-4-N-Fmoc-amino-L-proline Biological Activity

Description (2S,4R)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid is a proline derivative[1].
Related Catalog
In Vitro Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 650.2±55.0 °C at 760 mmHg
Melting Point 199ºC(lit.)
Molecular Formula C25H28N2O6
Molecular Weight 452.500
Flash Point 347.0±31.5 °C
Exact Mass 452.194733
PSA 105.17000
LogP 3.86
Appearance of Characters Powder | White/off-white/palebrown
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.627
Storage condition Store at 0-5°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases 22
Safety Phrases 36/37/38
RIDADR NONH for all modes of transport
WGK Germany 3

 Synthetic Route

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N-Boc-trans-4-N-Fmoc-amino-L-proline Structure

N-Boc-trans-4-N...

CAS#:176486-63-8

Literature: Zanardi, Franca; Burreddu, Paola; Rassu, Gloria; Auzzas, Luciana; Battistini, Lucia; Curti, Claudio; Sartori, Andrea; Nicastro, Giuseppe; Menchi, Gloria; Cini, Nicoletta; Bottonocetti, Anna; Raspanti, Silvia; Casiraghi, Giovanni Journal of Medicinal Chemistry, 2008 , vol. 51, # 6 p. 1771 - 1782

 Synonyms

(4R)-1-(tert-butoxycarbonyl)-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-L-proline
N-BOC-TRANS-4-N-FMOC-AMINO-L-PROLINE
RARECHEM EM WB 0068
(4R)-4-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-proline
1,2-Pyrrolidinedicarboxylic acid, 4-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, 1-(1,1-dimethylethyl) ester, (2S,4R)-
MFCD00673783
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