RU-SKI43 HCl

Modify Date: 2024-03-02 10:58:50

RU-SKI43 HCl Structure
RU-SKI43 HCl structure
Common Name RU-SKI43 HCl
CAS Number 1782573-67-4 Molecular Weight 423.012
Density N/A Boiling Point N/A
Molecular Formula C22H31ClN2O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RU-SKI43 HCl


RU-SKI 43 is an inhibitor of Hat. It blocks palmitoylation of Shh without affecting palmitoylation of H-Ras or Fyn, myristoylation of c-Src, or acylation of Wnt3a. RU-SKI-43 reduced pancreatic cancer cell proliferation and Gli-1 activation through Smoothened-independent non-canonical signaling. In addition, RU-SKI 43 treatment inhibited two key proliferative pathways regulated by Akt and mTOR.

 Names

Name RU-SKI 43 (hydrochloride)
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C22H31ClN2O2S
Molecular Weight 423.012
Exact Mass 422.179474

 Synonyms

2-[(2-Methylbutyl)amino]-1-{4-[(3-methylphenoxy)methyl]-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl}ethanone hydrochloride (1:1)
MFCD25371547
Ethanone, 1-[6,7-dihydro-4-[(3-methylphenoxy)methyl]thieno[3,2-c]pyridin-5(4H)-yl]-2-[(2-methylbutyl)amino]-, hydrochloride (1:1)
RU-SKI 43 (hydrochloride)