Revaprazan Hydrochloride

Modify Date: 2024-01-04 15:27:37

Revaprazan Hydrochloride Structure
Revaprazan Hydrochloride structure
Common Name Revaprazan Hydrochloride
CAS Number 178307-42-1 Molecular Weight 398.904
Density N/A Boiling Point N/A
Molecular Formula C22H24ClFN4 Melting Point 205-208°
MSDS N/A Flash Point N/A

 Use of Revaprazan Hydrochloride


Revaprazan hydrochloride is a novel acid pump antagonist (APA). Revaprazan hydrochloride reduces COX-2 expression and has significant anti-inflammatory actions activities in H. pylori infection[1].

 Names

Name Revaprazan Hydrochloride
Synonym More Synonyms

 Revaprazan Hydrochloride Biological Activity

Description Revaprazan hydrochloride is a novel acid pump antagonist (APA). Revaprazan hydrochloride reduces COX-2 expression and has significant anti-inflammatory actions activities in H. pylori infection[1].
Related Catalog
Target

Acid pump; COX-2[1]

References

[1]. Lee JS, et al. Revaprazan, a novel acid pump antagonist, exerts anti-inflammatory action against Helicobacter pylori-induced COX-2 expression by inactivating Akt signaling. J Clin Biochem Nutr. 2012 Sep;51(2):77-83.

 Chemical & Physical Properties

Melting Point 205-208°
Molecular Formula C22H24ClFN4
Molecular Weight 398.904
Exact Mass 398.167358
PSA 41.05000
LogP 6.03980
Storage condition 2-8°C

 Synonyms

T66 CNT&J B1 C- DT6N CNJ BMR DF& E1 F1 &&HCl
N-(4-Fluorophenyl)-4,5-dimethyl-6-(1-methyl-3,4-dihydro-2(1H)-isoquinolinyl)-2-pyrimidinamine hydrochloride (1:1)
4-(3,4-Dihydro-1-methyl-2(1H)-isoquinolinyl)-N-(4-fluorophenyl)-5,6-dimethyl-2-pyrimidinamine, monohydrochloride
N-(4-Fluorophenyl)-4,5-dimethyl-6-(1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)pyrimidin-2-amine hydrochloride
Revanex
2-Pyrimidinamine, 4-(3,4-dihydro-1-methyl-2(1H)-isoquinolinyl)-N-(4-fluorophenyl)-5,6-dimethyl-, monohydrochloride
Revaprazan HCL
2-Pyrimidinamine, 4-(3,4-dihydro-1-methyl-2(1H)-isoquinolinyl)-N-(4-fluorophenyl)-5,6-dimethyl-, hydrochloride (1:1)
YH1885
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