1-PALMITOYL(D31)-2-OLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Modify Date: 2024-01-06 09:53:17

1-PALMITOYL(D31)-2-OLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Structure
1-PALMITOYL(D31)-2-OLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE structure
Common Name 1-PALMITOYL(D31)-2-OLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
CAS Number 179093-76-6 Molecular Weight 791.267
Density N/A Boiling Point N/A
Molecular Formula C42H51D31NO8P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1-PALMITOYL(D31)-2-OLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE


1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d31 is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for

 Names

Name (2R)-3-[(2H31)Hexadecanoyloxy]-2-[(9Z)-9-octadecenoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
Synonym More Synonyms

  Biological Activity

Description 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC-d31 is deuterium labeled 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (POPC), a phospholipid, is a major component of biological membranes. 1-Palmitoyl-2-oleoyl-sn-glycero-3-PC is used for
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[2].
References

[1]. Moreno MJ, et al. Translocation of phospholipids and dithionite permeability in liquid-ordered and liquid-disordered membranes. Biophys J. 2006 Aug 1;91(3):873-81.

[2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

 Chemical & Physical Properties

Molecular Formula C42H51D31NO8P
Molecular Weight 791.267
Exact Mass 790.772400
LogP 11.42

 Synonyms

Ethanaminium, 2-[[hydroxy[(2R)-3-[(1-oxohexadecyl-2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13,14,14,15,15,16,16,16-d)oxy]-2-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]propoxy]phosphinyl]oxy]-N, 
N,N-trimethyl-, inner salt
(2R)-3-[(H)Hexadecanoyloxy]-2-[(9Z)-9-octadecenoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
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