2,5-Dihydroxycinnamic Acid phenethyl ester

Modify Date: 2024-01-20 13:25:00

2,5-Dihydroxycinnamic Acid phenethyl ester Structure
2,5-Dihydroxycinnamic Acid phenethyl ester structure
Common Name 2,5-Dihydroxycinnamic Acid phenethyl ester
CAS Number 179691-97-5 Molecular Weight 284.31
Density 1.3±0.1 g/cm3 Boiling Point 515.5±50.0 °C at 760 mmHg
Molecular Formula C17H16O4 Melting Point N/A
MSDS N/A Flash Point 192.2±23.6 °C

 Use of 2,5-Dihydroxycinnamic Acid phenethyl ester


5-LOX-IN-2, an inhibitor of 5-lipoxygenase (5-LOX) with an IC50 of 0.33 μM, inhibits 5-LOX in a dose-dependent manner . 5-LOX-IN-2, reduces the cell viability of renal cancer cells and induces apoptosis, can be used for cancer research[1].

 Names

Name 2,5-Dihydroxycinnamic Acid phenethyl ester
Synonym More Synonyms

  Biological Activity

Description 5-LOX-IN-2, an inhibitor of 5-lipoxygenase (5-LOX) with an IC50 of 0.33 μM, inhibits 5-LOX in a dose-dependent manner . 5-LOX-IN-2, reduces the cell viability of renal cancer cells and induces apoptosis, can be used for cancer research[1].
Related Catalog
Target

5-LOX:0.33 μM (IC50)

References

[1]. Selka A, et.al. Discovery of a novel 2,5-dihydroxycinnamic acid-based 5-lipoxygenase inhibitor that induces apoptosis and may impair autophagic flux in RCC4 renal cancer cells. Eur J Med Chem. 2019 Oct 1;179:347-357.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 515.5±50.0 °C at 760 mmHg
Molecular Formula C17H16O4
Molecular Weight 284.31
Flash Point 192.2±23.6 °C
Exact Mass 284.104858
LogP 3.70
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.646

 Synonyms

2-Phenylethyl (2E)-3-(2,5-dihydroxyphenyl)acrylate
2-phenylethyl (2E)-3-(2,5-dihydroxyphenyl)prop-2-enoate
β-Phenylethyl 2,5-dihydroxycinnamate
2-Propenoic acid, 3-(2,5-dihydroxyphenyl)-, 2-phenylethyl ester, (2E)-