A812511

Modify Date: 2024-01-13 16:54:43

A812511 Structure
A812511 structure
Common Name A812511
CAS Number 179985-52-5 Molecular Weight 225.25
Density 1.24g/cm3 Boiling Point 489.7ºC at 760 mmHg
Molecular Formula C13H11N3O Melting Point 200-202ºC
MSDS N/A Flash Point 250ºC

 Use of A812511


PKA-IN-1 is a potent and selective cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor with an IC50 of 0.03 μM[1].

 Names

Name N-(4-cyano-3-methylisoquinolin-1-yl)acetamide
Synonym More Synonyms

 A812511 Biological Activity

Description PKA-IN-1 is a potent and selective cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor with an IC50 of 0.03 μM[1].
Related Catalog
Target

IC50: 0.03 μM (cAK)[1]

References

[1]. Z X Lu, et al. Selective inhibition of cyclic AMP-dependent protein kinase by isoquinoline derivative. Biol Chem Hoppe Seyler. 1996 Jun;377(6):373-8

 Chemical & Physical Properties

Density 1.24g/cm3
Boiling Point 489.7ºC at 760 mmHg
Melting Point 200-202ºC
Molecular Formula C13H11N3O
Molecular Weight 225.25
Flash Point 250ºC
Exact Mass 225.09000
PSA 65.78000
LogP 2.44628
Vapour Pressure 9.74E-10mmHg at 25°C
Index of Refraction 1.632

 Synonyms

1-ACETAMIDO-4-CYANO-3-METHYLISOQUINOLINE
1-Acetamido-3-methyl-4-cyanosoquinoline
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