KL-1333(NQO1 activator 1)
Modify Date: 2024-01-13 22:56:33
KL-1333(NQO1 activator 1) structure
|
Common Name | KL-1333(NQO1 activator 1) | ||
|---|---|---|---|---|
| CAS Number | 1800405-30-4 | Molecular Weight | 240.26 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C14H12N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of KL-1333(NQO1 activator 1)NQO1 activator 1 is an orally available NAD+ modulator. It reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. Elevated NAD+ levels triggers the activation of SIRT1 and AMPK, and subsequently activates PGC-1α. NQO1 activator 1 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts[1]. |
| Name | NQO1 activator 1 |
|---|
| Description | NQO1 activator 1 is an orally available NAD+ modulator. It reacts with NAD(P)H:quinone oxidoreductase 1 (NQO1) as a substrate, resulting in increases in intracellular NAD+ levels via NADH oxidation. Elevated NAD+ levels triggers the activation of SIRT1 and AMPK, and subsequently activates PGC-1α. NQO1 activator 1 improves energy metabolism and mitochondrial dysfunction in MELAS fibroblasts[1]. |
|---|---|
| Related Catalog | |
| Target |
NQO1[1] |
| References |
| Molecular Formula | C14H12N2O2 |
|---|---|
| Molecular Weight | 240.26 |