Mc-VC-PAB-SN38

Modify Date: 2024-01-02 21:25:02

Mc-VC-PAB-SN38 Structure
Mc-VC-PAB-SN38 structure
Common Name Mc-VC-PAB-SN38
CAS Number 1801838-28-7 Molecular Weight 991.05
Density N/A Boiling Point N/A
Molecular Formula C51H58N8O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mc-VC-PAB-SN38


Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

 Names

Name Mc-VC-PAB-SN38

 Mc-VC-PAB-SN38 Biological Activity

Description Mc-VC-PAB-SN38 consists a cleavable ADC linker (Mc-VC-PAB) and a DNA topoisomerase I inhibitor (SN38). Mc-VC-PAB-SN38 can be used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog
Target

Camptothecins

In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

 Chemical & Physical Properties

Molecular Formula C51H58N8O13
Molecular Weight 991.05