MC-SN38 structure
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Common Name | MC-SN38 | ||
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CAS Number | 1473403-87-0 | Molecular Weight | 585.60 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C32H31N3O8 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of MC-SN38MC-SN38 is a drug-linker conjugate composed of a potent microtubule-disrupting agent SN38 and a non-cleavable MC linker to make antibody drug conjugate (ADC). SN-38, an active metabolite of the Topoisomerase I inhibitor Irinotecan, inhibits DNA synthesis and causes frequent DNA single-strand breaks[1][2]. |
Name | MC-SN38 |
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Description | MC-SN38 is a drug-linker conjugate composed of a potent microtubule-disrupting agent SN38 and a non-cleavable MC linker to make antibody drug conjugate (ADC). SN-38, an active metabolite of the Topoisomerase I inhibitor Irinotecan, inhibits DNA synthesis and causes frequent DNA single-strand breaks[1][2]. |
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Related Catalog | |
References |
Molecular Formula | C32H31N3O8 |
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Molecular Weight | 585.60 |
Hazard Codes | Xi |
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