MC-Sq-Cit-PAB-Gefitinib

Modify Date: 2024-01-11 13:44:32

MC-Sq-Cit-PAB-Gefitinib structure	Common Name	MC-Sq-Cit-PAB-Gefitinib
	CAS Number	1941168-63-3	Molecular Weight	1000.53
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₀H₆₁ClFN₁₀O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MC-Sq-Cit-PAB-Gefitinib

MC-Sq-Cit-PAB-Gefitinib has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Sq-Cit-PAB-Gefitinib is used for the antibody-drug conjugates (ADC) to treat various diseases or disorders, e.g. characterized by the overexpression of a tumor antigen[1,2].

Name	MC-Sq-Cit-PAB-Gefitinib

Description	MC-Sq-Cit-PAB-Gefitinib has a bioreversible linkage based on a quaternary ammonium for targeted delivery and it can improve pharmacokinetics and the therapeutic index. MC-Sq-Cit-PAB-Gefitinib is used for the antibody-drug conjugates (ADC) to treat various diseases or disorders, e.g. characterized by the overexpression of a tumor antigen[1,2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> Drug-Linker Conjugates for ADC
References	[1]. FLYGARE, John A, et al. Quaternary amine compounds and antibody-drug conjugates thereof. WO2016090050A1. [2]. Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> Drug-Linker Conjugates for ADC

References

[1]. FLYGARE, John A, et al. Quaternary amine compounds and antibody-drug conjugates thereof. WO2016090050A1.

[2]. Staben LR, et al. Targeted drug delivery through the traceless release of tertiary and heteroaryl amines from antibody-drug conjugates. Nat Chem. 2016 Dec;8(12):1112-1119.

Molecular Formula	C₅₀H₆₁ClFN₁₀O₉
Molecular Weight	1000.53

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: MC-Sq-Cit-PAB-Gefitinib
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

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MC-Sq-Cit-PAB-Gefitinib Biological Activity

Chemical & Physical Properties