CK2 inhibitor D11
Modify Date: 2024-02-03 14:14:24
CK2 inhibitor D11 structure
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Common Name | CK2 inhibitor D11 | ||
|---|---|---|---|---|
| CAS Number | 1803427-24-8 | Molecular Weight | 402.227 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H13Cl2NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CK2 inhibitor D11A potent, selective, cell permeab anti-apoptotic protein kinase CK2 with Ki of 5 nM; potently inhibits CK2α with IC50 of 7 nM, shows <2% remaining kinase activity against a panel of 354 eukaryotic protein kinases with exception of DYRK1B, PIM3 and IRAK1 (IC50=20-50 nM); inhibits the phosphorylation of the CK2 biomarker CDC37 at S13 in MIA PaCa-2 cells, also inhibits S380/T382/383 phosphorylation in PTEN in NSCLC cells. |
| Name | D11 |
|---|
| Description | A potent, selective, cell permeab anti-apoptotic protein kinase CK2 with Ki of 5 nM; potently inhibits CK2α with IC50 of 7 nM, shows <2% remaining kinase activity against a panel of 354 eukaryotic protein kinases with exception of DYRK1B, PIM3 and IRAK1 (IC50=20-50 nM); inhibits the phosphorylation of the CK2 biomarker CDC37 at S13 in MIA PaCa-2 cells, also inhibits S380/T382/383 phosphorylation in PTEN in NSCLC cells. |
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| References | References 1. Guerra B, et al. Mol Cell Biochem. 2015 Aug;406(1-2):151-61. View Related Products by Target Casein Kinase |
| Molecular Formula | C20H13Cl2NO4 |
|---|---|
| Molecular Weight | 402.227 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: CK2 inhibitor D11
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: CK2 inhibitor D11
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: CK2 inhibitor D11
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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