Mal-PEG5-NHS ester

Modify Date: 2024-01-02 18:16:22

Mal-PEG5-NHS ester Structure
Mal-PEG5-NHS ester structure
Common Name Mal-PEG5-NHS ester
CAS Number 1807537-42-3 Molecular Weight 486.470
Density 1.3±0.1 g/cm3 Boiling Point 608.4±65.0 °C at 760 mmHg
Molecular Formula C21H30N2O11 Melting Point N/A
MSDS N/A Flash Point 321.7±34.3 °C

 Use of Mal-PEG5-NHS ester


Mal-PEG5-NHS ester is an Alkyl/ether and PEG-based PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name 1-{18-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-18-oxo-3,6,9,12,15-pentaoxaoctadec-1-yl}-1H-pyrrole-2,5-dione
Synonym More Synonyms

 Mal-PEG5-NHS ester Biological Activity

Description Mal-PEG5-NHS ester is an Alkyl/ether and PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 608.4±65.0 °C at 760 mmHg
Molecular Formula C21H30N2O11
Molecular Weight 486.470
Flash Point 321.7±34.3 °C
Exact Mass 486.184967
LogP -3.32
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.541
Storage condition 2-8°C

 Synonyms

1-{18-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-18-oxo-3,6,9,12,15-pentaoxaoctadec-1-yl}-1H-pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 1-[18-[(2,5-dioxo-1-pyrrolidinyl)oxy]-18-oxo-3,6,9,12,15-pentaoxaoctadec-1-yl]-
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