EPZ-030456
Modify Date: 2024-01-18 21:14:05
EPZ-030456 structure
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Common Name | EPZ-030456 | ||
|---|---|---|---|---|
| CAS Number | 1808011-23-5 | Molecular Weight | 572.121 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H34ClN5O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EPZ-030456EPZ-030456 (EPZ030456) is a potent, selective SMYD3 inhibitor with biochem IC50 of 4 nM; displays noncompetitive inhibition with respect to SAM and MEKK2 with Ki of 1.2 and 1.1 nM, respectively; has cellular potency (IC50=48 nM) suitable to probe the in vitro biology of SMYD3 inhibition. |
| Name | EPZ-030456 |
|---|
| Description | EPZ-030456 (EPZ030456) is a potent, selective SMYD3 inhibitor with biochem IC50 of 4 nM; displays noncompetitive inhibition with respect to SAM and MEKK2 with Ki of 1.2 and 1.1 nM, respectively; has cellular potency (IC50=48 nM) suitable to probe the in vitro biology of SMYD3 inhibition. |
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| References | References 1. Mitchell LH, et al. ACS Med Chem Lett. 2015 Aug 27;7(2):134-8. View Related Products by Target Histone Methyltransferase (HMTase) |
| Molecular Formula | C28H34ClN5O4S |
|---|---|
| Molecular Weight | 572.121 |