(Met186)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse) trifluoroacetate salt

Modify Date: 2024-01-10 13:42:19

(Met186)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse) trifluoroacetate salt Structure
(Met186)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse) trifluoroacetate salt structure
Common Name (Met186)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse) trifluoroacetate salt
CAS Number 181477-43-0 Molecular Weight 1035.21
Density 1.3±0.1 g/cm3 Boiling Point 1450.7±65.0 °C at 760 mmHg
Molecular Formula C47H74N10O14S Melting Point N/A
MSDS N/A Flash Point 831.1±34.3 °C

 Use of (Met186)-Melanocyte Protein PMEL 17 (185-193) (human, bovine, mouse) trifluoroacetate salt


Disomotide (G209-2M) is a melanoma antigen that enhances the generation of cytotoxic T lymphocytes (CTL) recognizing native G209 as well as melanoma[1][2].

 Names

Name Disomotide
Synonym More Synonyms

  Biological Activity

Description Disomotide (G209-2M) is a melanoma antigen that enhances the generation of cytotoxic T lymphocytes (CTL) recognizing native G209 as well as melanoma[1][2].
Related Catalog
In Vitro 为了激活 Ag,用 Disomotide (G209-2M; 1 μM) 处理 PBMCs 6天[2]。
References

[1]. Yang S, et al. Antimelanoma activity of CTL generated from peripheral blood mononuclear cells after stimulation with autologous dendritic cells pulsed with melanoma gp100 peptide G209-2M is correlated to TCR avidity. J Immunol. 2002 Jul 1;169(1):531-9.  

[2]. Ahmadzadeh M, et al. IL-2 and IL-15 each mediate de novo induction of FOXP3 expression in human tumor antigen-specific CD8 T cells. J Immunother. 2007 Apr;30(3):294-302.  

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 1450.7±65.0 °C at 760 mmHg
Molecular Formula C47H74N10O14S
Molecular Weight 1035.21
Flash Point 831.1±34.3 °C
Exact Mass 1034.510620
PSA 413.25000
LogP 2.44
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.569

 Synonyms

disomotide
L-Isoleucyl-L-methionyl-L-α-aspartyl-L-glutaminyl-L-valyl-L-prolyl-L-phenylalanyl-L-seryl-L-valine
L-Valine, L-isoleucyl-L-methionyl-L-α-aspartyl-L-glutaminyl-L-valyl-L-prolyl-L-phenylalanyl-L-seryl-
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