Ethiprole

Modify Date: 2024-01-02 18:12:57

Ethiprole Structure
Ethiprole structure
Common Name Ethiprole
CAS Number 181587-01-9 Molecular Weight 397.20300
Density 1.69g/cm3 Boiling Point 563.5ºC at 760mmHg
Molecular Formula C13H9Cl2F3N4OS Melting Point ~174°
MSDS USA Flash Point 294.6ºC
Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Warning

 Use of Ethiprole


Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity[1].

 Names

Name ethiprole
Synonym More Synonyms

 Ethiprole Biological Activity

Description Ethiprole is an insecticide.Metabolic sulfones are produced faster than Fipronil (HY-B0822) in CYP3A4-expressing cells and in vivo in mouse brain and liver.Ethiprole's sulfide, sulfoxide, sulfone and desulfinyl derivatives have better biological activity[1].
Related Catalog
References

[1]. Caboni P, Sammelson RE, Casida JE. Phenylpyrazole insecticide photochemistry, metabolism, and GABAergic action: ethiprole compared with fipronil. J Agric Food Chem. 2003 Nov 19;51(24):7055-61.  

 Chemical & Physical Properties

Density 1.69g/cm3
Boiling Point 563.5ºC at 760mmHg
Melting Point ~174°
Molecular Formula C13H9Cl2F3N4OS
Molecular Weight 397.20300
Flash Point 294.6ºC
Exact Mass 395.98300
PSA 103.91000
LogP 5.22618
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.655
Storage condition 0-6°C

 Safety Information

Symbol GHS08 GHS09
GHS08, GHS09
Signal Word Warning
Hazard Statements H373-H410
Precautionary Statements P273-P501
Target Organs Liver, Thyroid.
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T,N
Risk Phrases R23/24/25
Safety Phrases S36/37
RIDADR UN2811 6.1/PG 3

 Synonyms

Ethiprole
UNII-5527E53JNB
5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethylsulfinyl)-1H-pyrazole-3-carbonitrile
5-amino-1-(2,6-dichloro-α,α,α-trifluoro-p-tolyl)-4-ethylsulfinylpyrazole-3-carbonitrile
5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-ethylsulfinylpyrazole-3-carbonitrile
5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-4-(ethanesulfinyl)-1H-pyrazole-3-carbonitrile
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Price: ¥450/50 mg

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