Carboxy-PEG5-sulfonic acid

Modify Date: 2024-01-10 06:05:06

Carboxy-PEG5-sulfonic acid Structure
Carboxy-PEG5-sulfonic acid structure
Common Name Carboxy-PEG5-sulfonic acid
CAS Number 1817735-38-8 Molecular Weight 374.40
Density N/A Boiling Point N/A
Molecular Formula C13H26O10S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Carboxy-PEG5-sulfonic acid


Carboxy-PEG5-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Carboxy-PEG5-sulfonic acid

 Carboxy-PEG5-sulfonic acid Biological Activity

Description Carboxy-PEG5-sulfonic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C13H26O10S
Molecular Weight 374.40