MC-VA-PABC-MMAE

Modify Date: 2024-01-13 21:43:30

MC-VA-PABC-MMAE structure	Common Name	MC-VA-PABC-MMAE
	CAS Number	1818864-51-5	Molecular Weight	1230.53
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₆₅H₉₉N₉O₁₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of MC-VA-PABC-MMAE

MC-VA-PABC-MMAE is a drug-linker conjugate for ADC. MC-VA-PABC-MMAE contains the ADCs linker (peptide MC-VA-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1][2].

Name	MC-VA-PABC-MMAE

Description	MC-VA-PABC-MMAE is a drug-linker conjugate for ADC. MC-VA-PABC-MMAE contains the ADCs linker (peptide MC-VA-PABC) and a potent tubulin polymerization inhibitor MMAE (HY-15162)[1][2].
Related Catalog	Research Areas >> Cancer
Target	Auristatin
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Wang Y, et al. Development of applicable thiol-linked antibody-drug conjugates with improved stability and therapeutic index. Drug Deliv. 2022 Dec;29(1):754-766. [2]. Cazzamalli S, et al. Linker stability influences the anti-tumor activity of acetazolamide-drug conjugates for the therapy of renal cell carcinoma. J Control Release. 2017 Jan 28;246:39-45.

Molecular Formula	C₆₅H₉₉N₉O₁₄
Molecular Weight	1230.53

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: MC-VA-PABC-MMAE
Price: Negotiable
Purity: 99.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: MC-VA-PABC-MMAE
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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