S-Acetyl-peg2-t-butyl ester

Modify Date: 2024-01-03 19:01:40

S-Acetyl-peg2-t-butyl ester Structure
S-Acetyl-peg2-t-butyl ester structure
Common Name S-Acetyl-peg2-t-butyl ester
CAS Number 1820641-93-7 Molecular Weight 292.39
Density N/A Boiling Point N/A
Molecular Formula C13H24O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of S-Acetyl-peg2-t-butyl ester


S-acetyl-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name S-acetyl-PEG2-Boc
Synonym More Synonyms

 S-Acetyl-peg2-t-butyl ester Biological Activity

Description S-acetyl-PEG2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C13H24O5S
Molecular Weight 292.39

 Synonyms

MFCD22574783