Rolziracetam

Modify Date: 2024-01-11 16:35:31

Rolziracetam Structure
Rolziracetam structure
 Common Name Rolziracetam
CAS Number 18356-28-0 Molecular Weight 139.15200
Density 1.28g/cm3 Boiling Point 274.9ºC at 760mmHg
Molecular Formula C7H9NO2 Melting Point N/A
MSDS N/A Flash Point 130.5ºC

 Use of Rolziracetam


Rolziracetam is a nootropic drug of the racetam family and improves short-term memory in rats and monkeys[1].

 Names

Name 2,6,7,8-tetrahydro-1H-pyrrolizine-3,5-dione
Synonym More Synonyms

 Rolziracetam Biological Activity

Description Rolziracetam is a nootropic drug of the racetam family and improves short-term memory in rats and monkeys[1].
Related Catalog
References

[1]. Schindler U, et al. Pre-clinical evaluation of cognition enhancing drugs. Prog Neuropsychopharmacol Biol Psychiatry. 1989;13 Suppl:S99-115.

 Chemical & Physical Properties

Density 1.28g/cm3
Boiling Point 274.9ºC at 760mmHg
Molecular Formula C7H9NO2
Molecular Weight 139.15200
Flash Point 130.5ºC
Exact Mass 139.06300
PSA 37.38000
LogP 0.23570
Vapour Pressure 0.00526mmHg at 25°C
Index of Refraction 1.548
Storage condition 2-8℃

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UY8000000
CHEMICAL NAME :
1H-Pyrrolizine-3,5(2H,6H)-dione, dihydro-
CAS REGISTRY NUMBER :
18356-28-0
BEILSTEIN REFERENCE NO. :
0121236
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C7-H9-N-O2
MOLECULAR WEIGHT :
139.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
7 gm/kg/14D-I
TOXIC EFFECTS :
Liver - other changes Kidney, Ureter, Bladder - other changes Musculoskeletal - other changes
REFERENCE :
TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 17,545,1989

 Safety Information

HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

CI-911
tetrahydro-6H-pyrrolizine-3,5-dione
tetrahydro-pyrrolizine-3,5-dione
Rolziracetam
3,5-Dioxopyrrolizidine
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