1-isothiocyanato-PEG4-Alcohol

Modify Date: 2024-01-23 10:26:56

1-isothiocyanato-PEG4-Alcohol Structure
1-isothiocyanato-PEG4-Alcohol structure
Common Name 1-isothiocyanato-PEG4-Alcohol
CAS Number 1835759-69-7 Molecular Weight 235.30
Density N/A Boiling Point N/A
Molecular Formula C9H17NO4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1-isothiocyanato-PEG4-Alcohol


1-Isothiocyanato-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1-Isothiocyanato-PEG4-alcohol
Synonym More Synonyms

 1-isothiocyanato-PEG4-Alcohol Biological Activity

Description 1-Isothiocyanato-PEG4-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C9H17NO4S
Molecular Weight 235.30

 Synonyms

MFCD29052173