1,1,1-Trifluoroethyl-peg5-tos

Modify Date: 2024-01-04 16:36:44

1,1,1-Trifluoroethyl-peg5-tos structure	Common Name	1,1,1-Trifluoroethyl-peg5-tos
	CAS Number	1872433-61-8	Molecular Weight	430.44
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₇H₂₅F₃O₇S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 1,1,1-Trifluoroethyl-peg5-tos

1,1,1-Trifluoroethyl-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1,1,1-Trifluoroethyl-PEG4-Tos
Synonym	More Synonyms

Description	1,1,1-Trifluoroethyl-PEG4-Tos is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₁₇H₂₅F₃O₇S
Molecular Weight	430.44

MFCD29079383