NF 1819
Modify Date: 2024-01-12 12:21:00
NF 1819 structure
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Common Name | NF 1819 | ||
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| CAS Number | 1881244-28-5 | Molecular Weight | 463.46 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 660.5±65.0 °C at 760 mmHg | |
| Molecular Formula | C24H22FN5O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 353.2±34.3 °C | |
Use of NF 1819MGL-IN-1 is a potent and selective irreversible MGL (β-lactam-based monoacylglycerol lipase) inhibitor. MGL-IN-1 alleviates symptoms in a MS model in vivo and exhibits analgesic effects in an acute inflammatory pain model in vivo. MGL-IN-1 displays high membrane permeability and brain penetrant[1]. |
| Name | (3R,4S)-4-(1,3-Benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1H-1,2,4-triazol-1-ylcarbonyl)-4-piperidinyl]-2-azetidinone |
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| Synonym | More Synonyms |
| Description | MGL-IN-1 is a potent and selective irreversible MGL (β-lactam-based monoacylglycerol lipase) inhibitor. MGL-IN-1 alleviates symptoms in a MS model in vivo and exhibits analgesic effects in an acute inflammatory pain model in vivo. MGL-IN-1 displays high membrane permeability and brain penetrant[1]. |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 660.5±65.0 °C at 760 mmHg |
| Molecular Formula | C24H22FN5O4 |
| Molecular Weight | 463.46 |
| Flash Point | 353.2±34.3 °C |
| Exact Mass | 463.165588 |
| LogP | 1.14 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.735 |
| MFCD31544489 |
| (3R,4S)-4-(1,3-Benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1H-1,2,4-triazol-1-ylcarbonyl)-4-piperidinyl]-2-azetidinone |
| 2-Azetidinone, 4-(1,3-benzodioxol-5-yl)-3-(4-fluorophenyl)-1-[1-(1H-1,2,4-triazol-1-ylcarbonyl)-4-piperidinyl]-, (3R,4S)- |