frakefamide
Modify Date: 2024-01-03 13:13:24
frakefamide structure
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Common Name | frakefamide | ||
|---|---|---|---|---|
| CAS Number | 188196-22-7 | Molecular Weight | 563.620 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 897.9±65.0 °C at 760 mmHg | |
| Molecular Formula | C30H34FN5O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 496.8±34.3 °C | |
Use of frakefamideFrakefamide is a potent analgesic that acts as a peripheral active μ-selective receptor agonist. Frakefamide is unable to penetrate the blood-brain-barrier and enter the central nervous system[1][2]. |
| Name | frakefamide |
|---|---|
| Synonym | More Synonyms |
| Description | Frakefamide is a potent analgesic that acts as a peripheral active μ-selective receptor agonist. Frakefamide is unable to penetrate the blood-brain-barrier and enter the central nervous system[1][2]. |
|---|---|
| Related Catalog | |
| In Vivo | Frakefamide (LEF576) yields a dose dependent increase in morphine appropriate responding to 50% at the highest dose tested (10 μmol/kg) after infusion durations of 2 min, whereas after 15 min infusions a maximum of 25% morphine appropriate responding was occasioned at 17.5 μmol/kg[1][2]. |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 897.9±65.0 °C at 760 mmHg |
| Molecular Formula | C30H34FN5O5 |
| Molecular Weight | 563.620 |
| Flash Point | 496.8±34.3 °C |
| Exact Mass | 563.254395 |
| LogP | 1.45 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.610 |
| L-Phenylalaninamide, 4-fluoro-L-phenylalanyl-N-[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-1-oxopropyl]- |
| 4-Fluoro-L-phenylalanyl-N-[(2R)-2-(L-tyrosylamino)propanoyl]-L-phenylalaninamide |
| frakefamide |