3-(p-fluorophenyl)-2-methyl-4(3h)-quinazolinon

Modify Date: 2024-07-18 15:20:09

3-(p-fluorophenyl)-2-methyl-4(3h)-quinazolinon structure	Common Name	3-(p-fluorophenyl)-2-methyl-4(3h)-quinazolinon
	CAS Number	1897-80-9	Molecular Weight	254.25900
	Density	1.25g/cm3	Boiling Point	411.4ºC at 760mmHg
	Molecular Formula	C₁₅H₁₁FN₂O	Melting Point	N/A
	MSDS	N/A	Flash Point	202.6ºC

Use of 3-(p-fluorophenyl)-2-methyl-4(3h)-quinazolinon

WAY-622252 is an active molecule for the study of amyloid diseases and synucleinopathies.

Name	3-(4-fluorophenyl)-2-methylquinazolin-4-one
Synonym	More Synonyms

Description	WAY-622252 is an active molecule for the study of amyloid diseases and synucleinopathies.
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others

Density	1.25g/cm3
Boiling Point	411.4ºC at 760mmHg
Molecular Formula	C₁₅H₁₁FN₂O
Molecular Weight	254.25900
Flash Point	202.6ºC
Exact Mass	254.08600
PSA	34.89000
LogP	2.83320
Vapour Pressure	5.62E-07mmHg at 25°C
Index of Refraction	1.621

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VA3408000

CHEMICAL NAME :: 4(3H)-Quinazolinone, 3-(p-fluorophenyl)-2-methyl-

CAS REGISTRY NUMBER :: 1897-80-9

BEILSTEIN REFERENCE NO. :: 0886566

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C15-H11-F-N2-O

MOLECULAR WEIGHT :: 254.28

WISWESSER LINE NOTATION :: T66 BVN ENJ CR DF& E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 13,688,1963

4-FLUOROANILINE HCL

CAS#:2146-07-8

Acetamide,N-(2-...

CAS#:25116-00-1

~36%

3-(p-fluorophen...

CAS#:1897-80-9

Literature: Hilmy, Khalid Mohamed Hassan; Mogensen, Joergen; Pedersen, Erik B. Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, p. 467 - 468

2-Methyl-3,1-be...

CAS#:525-76-8

4-Fluoroaniline

CAS#:371-40-4

~53%

3-(p-fluorophen...

CAS#:1897-80-9

Literature: Mahindroo, Neeraj; Ahmed, Zabeer; Bhagat, Asha; Bedi, Kasturi Lal; Khajuria, Ravi Kant; Kapoor, Vijay Kumar; Dhar, Kanaya Lal Medicinal Chemistry Research, 2005 , vol. 14, # 6 p. 347 - 368