BIIL-260 hydrochloride
Modify Date: 2024-01-03 18:18:55
BIIL-260 hydrochloride structure
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Common Name | BIIL-260 hydrochloride | ||
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| CAS Number | 192581-24-1 | Molecular Weight | 503.03 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C30H31ClN2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BIIL-260 hydrochlorideBIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB4 antagonist, with anti-inflammatory activity. BIIL-260 hydrochloride interacts with the LTB4 receptor in a saturable, reversible, and competitive manner, has high affinity to the LTB4 receptor on isolated human neutrophil cell membranes with Ki values of 1.7 nM[1]. |
| Name | BIIL-260 hydrochloride |
|---|
| Description | BIIL-260 hydrochloride is a potent and long-acting orally active leukotriene B(4) receptor LTB4 antagonist, with anti-inflammatory activity. BIIL-260 hydrochloride interacts with the LTB4 receptor in a saturable, reversible, and competitive manner, has high affinity to the LTB4 receptor on isolated human neutrophil cell membranes with Ki values of 1.7 nM[1]. |
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| Related Catalog | |
| Target |
Ki: 1.7 nM (LTB4 receptor)[1] |
| In Vitro | BIIL-260 hydrochloride potently inhibits LTB4-induced intracellular Ca2+ release in human neutrophils with IC50 value of 0.82 nM |
| References |
| Molecular Formula | C30H31ClN2O3 |
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| Molecular Weight | 503.03 |