CDC801

Modify Date: 2024-01-09 08:35:37

CDC801 Structure
CDC801 structure
Common Name CDC801
CAS Number 192819-27-5 Molecular Weight 408.45
Density N/A Boiling Point N/A
Molecular Formula C23H24N2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CDC801


CDC801 is a potent and orally active phosphodiesterase 4 (PDE4) and tumor necrosis factor-α (TNF-α) inhibitor with IC50 of 1.1 μM and 2.5 μM, respectively.

 Names

Name CDC801

 CDC801 Biological Activity

Description CDC801 is a potent and orally active phosphodiesterase 4 (PDE4) and tumor necrosis factor-α (TNF-α) inhibitor with IC50 of 1.1 μM and 2.5 μM, respectively.
Related Catalog
Target

IC50: 1.1μM (PDE4), 2.5μM (TNF-α)[1]

In Vitro The more detailed information refer to the Compound 6b in the reference 1 (PMID:19256507)[1].
References

[1]. Man HW, et al. Discovery of (S)-N-[2-[1-(3-ethoxy-4-methoxyphenyl)-2-methanesulfonylethyl]-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl] acetamide (apremilast), a potent and orally active phosphodiesterase 4and tumor necrosis factor-alpha inhibitor. J Med Chem. 2009 Mar 26;52(6):1522-4.

 Chemical & Physical Properties

Molecular Formula C23H24N2O5
Molecular Weight 408.45
Storage condition 2-8℃