Zeylenone

Modify Date: 2024-01-12 10:00:28

Zeylenone structure	Common Name	Zeylenone
	CAS Number	193410-84-3	Molecular Weight	382.363
	Density	1.4±0.1 g/cm3	Boiling Point	569.6±50.0 °C at 760 mmHg
	Molecular Formula	C₂₁H₁₈O₇	Melting Point	150-152℃
	MSDS	N/A	Flash Point	201.4±23.6 °C

Use of Zeylenone

Zeylenone, isolated from ethanol extract of the leaves of Uvaria grandiflora Roxb. Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways[1].

Name	[(1S,5R,6S)-5-benzoyloxy-1,6-dihydroxy-2-oxocyclohex-3-en-1-yl]methyl benzoate
Synonym	More Synonyms

Description	Zeylenone, isolated from ethanol extract of the leaves of Uvaria grandiflora Roxb. Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Zhang L, et al. Zeylenone, a naturally occurring cyclohexene oxide, inhibits proliferation and induces apoptosis in cervical carcinoma cells via PI3K/AKT/mTOR and MAPK/ERK pathways. Sci Rep. 2017 May 10;7(1):1669.

Density	1.4±0.1 g/cm3
Boiling Point	569.6±50.0 °C at 760 mmHg
Melting Point	150-152℃
Molecular Formula	C₂₁H₁₈O₇
Molecular Weight	382.363
Flash Point	201.4±23.6 °C
Exact Mass	382.105255
PSA	110.13000
LogP	3.78
Vapour Pressure	0.0±1.6 mmHg at 25°C
Index of Refraction	1.642