Fmoc-Aeg(N3)-OH

Modify Date: 2024-09-15 23:31:50

Fmoc-Aeg(N3)-OH Structure
Fmoc-Aeg(N3)-OH structure
Common Name Fmoc-Aeg(N3)-OH
CAS Number 1935981-35-3 Molecular Weight 366.37
Density N/A Boiling Point N/A
Molecular Formula C19H18N4O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Fmoc-Aeg(N3)-OH


Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis[1].

 Names

Name Fmoc-Aeg(N3)-OH

 Fmoc-Aeg(N3)-OH Biological Activity

Description Fmoc-Aeg(N3)-OH is a click chemistry reagent containing an Azide. Alkylating the Nitrogen of an amide bond results in peptoid structures, which leads to conformational restrains, like N-methylation and allows backbone derivatisation. Altering cytotoxicity, bacterial cell selectivity and receptor pharmacology through formation of peptoid derivatives have been published for Cilengitide, Piscidin 1, and MC3, MC4 and MC5 receptor agonist. This building block enables design of macrocycles through intermolecular crosslinking or backbone stabilization through intermolecular ring-closure. This compound is a potential building block for the construction of (customized) peptide nucleic acids (PNAs) and for peptoid synthesis[1].
Related Catalog

 Chemical & Physical Properties

Molecular Formula C19H18N4O4
Molecular Weight 366.37