CP-409092

Modify Date: 2024-01-09 15:49:25

CP-409092 Structure
CP-409092 structure
Common Name CP-409092
CAS Number 194098-25-4 Molecular Weight 297.352
Density 1.3±0.1 g/cm3 Boiling Point 475.0±45.0 °C at 760 mmHg
Molecular Formula C17H19N3O2 Melting Point N/A
MSDS N/A Flash Point 241.1±28.7 °C

 Use of CP-409092


CP-409092 is a GABA(A) partial agonist, used for the treatment of anxiety.

 Names

Name CP-409092
Synonym More Synonyms

 CP-409092 Biological Activity

Description CP-409092 is a GABA(A) partial agonist, used for the treatment of anxiety.
Related Catalog
In Vivo The pharmacokinetics of CP-409,092 following single intravenous and oral doses of 4 and 15 mg/kg, respectively, are characterized by high clearance of 169+ or -18 mL/min/kg, a volume of distribution of 8.99+ or -1.46 L/kg, and an oral bioavailability of 2.9%+ or -3%. Following oral administration of 100 mg/kg [14C]CP-409,092, the total recovery is 89.1%+ or -3.2% for male rats and 89.3%+ or -0.58% for female rats[1].
References

[1]. Kamel A, et al. Metabolism, pharmacokinetics and excretion of the GABA(A) receptor partial agonist [(14)C]CP-409,092 in rats. Xenobiotica. 2010 Jun;40(6):400-14.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 475.0±45.0 °C at 760 mmHg
Molecular Formula C17H19N3O2
Molecular Weight 297.352
Flash Point 241.1±28.7 °C
Exact Mass 297.147736
LogP 0.85
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.658

 Synonyms

420WLS764W
CP-409092
1H-Indole-3-carboxamide, 4,5,6,7-tetrahydro-N-[4-[(methylamino)methyl]phenyl]-4-oxo-
N-{4-[(Methylamino)methyl]phenyl}-4-oxo-4,5,6,7-tetrahydro-1H-indole-3-carboxamide
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