CB-03-01
Modify Date: 2024-01-02 22:15:36
CB-03-01 structure
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Common Name | CB-03-01 | ||
|---|---|---|---|---|
| CAS Number | 19608-29-8 | Molecular Weight | 402.524 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 538.9±50.0 °C at 760 mmHg | |
| Molecular Formula | C24H34O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 179.3±23.6 °C | |
Use of CB-03-01Cortexolone 17 alpha-propionate(CB-03-01) is a new topical and peripherally selective androgen antagonist. IC50 value:Target: Androgen ReceptorCortexolone 17 alpha-propionate (CB-03-01) is a new potent topical antiandrogen potentially useful in acne vulgaris. CB-03-01 1% cream was very well tolerated, and was significantly better than placebo regarding TLC (P = 0·0017), ILC (P = 0·0134) and ASI (P = 0·0090), and also clinically more effective than comparator. The product also induced a faster attainment of 50% improvement in all the above parameters. |
| Name | 21-Hydroxy-17-(1-oxopropoxy)pregn-4-ene-3,20-dione |
|---|---|
| Synonym | More Synonyms |
| Description | Cortexolone 17 alpha-propionate(CB-03-01) is a new topical and peripherally selective androgen antagonist. IC50 value:Target: Androgen ReceptorCortexolone 17 alpha-propionate (CB-03-01) is a new potent topical antiandrogen potentially useful in acne vulgaris. CB-03-01 1% cream was very well tolerated, and was significantly better than placebo regarding TLC (P = 0·0017), ILC (P = 0·0134) and ASI (P = 0·0090), and also clinically more effective than comparator. The product also induced a faster attainment of 50% improvement in all the above parameters. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 538.9±50.0 °C at 760 mmHg |
| Molecular Formula | C24H34O5 |
| Molecular Weight | 402.524 |
| Flash Point | 179.3±23.6 °C |
| Exact Mass | 402.240631 |
| PSA | 80.67000 |
| LogP | 3.76 |
| Vapour Pressure | 0.0±3.3 mmHg at 25°C |
| Index of Refraction | 1.555 |
| cortexolone 17α-propionate |
| [(8R,9S,10R,13S,14S,17R)-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate |
| Pregn-4-ene-3,20-dione, 21-hydroxy-17-(1-oxopropoxy)- |
| 21-Hydroxy-3,20-dioxopregn-4-en-17-yl propionate |
| CB-03-01 |
| Cortexolone 17 alpha-propionate |