Laniquidar
Modify Date: 2024-01-07 20:28:25
Laniquidar structure
|
Common Name | Laniquidar | ||
|---|---|---|---|---|
| CAS Number | 197509-46-9 | Molecular Weight | 584.71 | |
| Density | 1.24g/cm3 | Boiling Point | 793.1ºC at 760mmHg | |
| Molecular Formula | C37H36N4O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 433.5ºC | |
Use of LaniquidarLaniquidar (R101933) is a noncompetitive, third generation P-glycoprotein (P-gp) inhibitor with an IC50 of 0.51 μM. Laniquidar can be used for modulating multidrug resistance transporters[1]. Laniquidar can also be used for studying acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)[2]. Laniquidar has limited oral bioavailability[3]. |
| Name | methyl 11-[1-[2-[4-(quinolin-2-ylmethoxy)phenyl]ethyl]piperidin-4-ylidene]-5,6-dihydroimidazo[2,1-b][3]benzazepine-3-carboxylate |
|---|---|
| Synonym | More Synonyms |
| Description | Laniquidar (R101933) is a noncompetitive, third generation P-glycoprotein (P-gp) inhibitor with an IC50 of 0.51 μM. Laniquidar can be used for modulating multidrug resistance transporters[1]. Laniquidar can also be used for studying acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS)[2]. Laniquidar has limited oral bioavailability[3]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 0.51 μM (P-glycoprotein)[1] |
| References |
| Density | 1.24g/cm3 |
|---|---|
| Boiling Point | 793.1ºC at 760mmHg |
| Molecular Formula | C37H36N4O3 |
| Molecular Weight | 584.71 |
| Flash Point | 433.5ºC |
| Exact Mass | 584.27900 |
| PSA | 69.48000 |
| LogP | 6.43130 |
| Vapour Pressure | 3.83E-25mmHg at 25°C |
| Index of Refraction | 1.659 |
| Laniquidar |
| 5H-Imidazo(2,1-b)(3)benzazepine-3-carboxylic acid,6,11-dihydro-11-(1-(2-(4-(2-quinolinylmethoxy)phenyl)ethyl)-4-piperidinylidene)-,methyl ester |
| Laniquidar [INN] |
| UNII-K3FRN4DDOY |