3-Chloro-4-pyridinamine

Modify Date: 2024-01-03 16:39:32

3-Chloro-4-pyridinamine Structure
3-Chloro-4-pyridinamine structure
Common Name 3-Chloro-4-pyridinamine
CAS Number 19798-77-7 Molecular Weight 128.560
Density 1.3±0.1 g/cm3 Boiling Point 250.9±20.0 °C at 760 mmHg
Molecular Formula C5H5ClN2 Melting Point 44-46ºC
MSDS USA Flash Point 105.5±21.8 °C

 Names

Name 3-chloropyridin-4-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 250.9±20.0 °C at 760 mmHg
Melting Point 44-46ºC
Molecular Formula C5H5ClN2
Molecular Weight 128.560
Flash Point 105.5±21.8 °C
Exact Mass 128.014130
PSA 38.91000
LogP 1.48
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.607

 MSDS

Material Safety Data Sheet

Section1. Identification of the substance
Product Name: 4-Amino-3-chloropyridine
Synonyms:

Section2. Hazards identification
Harmful by inhalation, in contact with skin, and if swallowed.
H302:Harmful if swallowed
H312:Harmful in contact with skin
H332:Harmful if inhaled
H315:Causes skin irritation
H319:Causes serious eye irritation
H335:May cause respiratory irritation
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present
and easy to do – continue rinsing

Section3. Composition/information on ingredients.
Ingredient name:4-Amino-3-chloropyridine
CAS number:19798-77-7

Section4. First aid measures
Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing
contaminated clothing and shoes. If irritation persists, seek medical attention.
Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate
flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical
attention.
Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention.
Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention.

Section5. Fire fighting measures
In the event of a fire involving this material, alone or in combination with other materials, use dry
powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus
should be worn.

Section6. Accidental release measures
Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national
standards.
Respiratory precaution:Wear approved mask/respirator
Hand precaution:Wear suitable gloves/gauntlets
Skin protection:Wear suitable protective clothing
Eye protection:Wear suitable eye protection
Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container
for disposal. See section 12.
Environmental precautions: Do not allow material to enter drains or water courses.

Section7. Handling and storage
Handling:This product should be handled only by, or under the close supervision of, those properly qualified
in the handling and use of potentially hazardous chemicals, who should take into account the fire,
health and chemical hazard data given on this sheet.
Storage:Store in closed vessels.

Section8. Exposure Controls / Personal protection
Engineering Controls: Use only in a chemical fume hood.
Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles.
General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse.

Section9. Physical and chemical properties
Not specified
Appearance:
Boiling point:No data
Melting point:No data
Flash point:No data
Density:No data
Molecular formula:C5H5ClN2
Molecular weight:128.6

Section10. Stability and reactivity
Conditions to avoid: Heat, flames and sparks.
Materials to avoid: Oxidizing agents.
Possible hazardous combustion products: Carbon monoxide, nitrogen oxides, hydrogen chloride.

Section11. Toxicological information
No data.

Section12. Ecological information
No data.

Section13. Disposal consideration
Arrange disposal as special waste, by licensed disposal company, in consultation with local waste
disposal authority, in accordance with national and regional regulations.

Section14. Transportation information
Non-harzardous for air and ground transportation.

Section15. Regulatory information
No chemicals in this material are subject to the reporting requirements of SARA Title III, Section
302, or have known CAS numbers that exceed the threshold reporting levels established by SARA
Title III, Section 313.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S26
HS Code 2933399090

 Synthetic Route

~36%

3-Chloro-4-pyridinamine Structure

3-Chloro-4-pyri...

CAS#:19798-77-7

Literature: Cook, David C.; Jones, Ronald H.; Kabir, Humayun; Lythgoe, David J.; McFarlane, Ian M.; Pemberton, Clive; Thatcher, Alan A.; Thompson, David M.; Walton, John B. Organic Process Research and Development, 1998 , vol. 2, # 3 p. 157 - 168

~16%

3-Chloro-4-pyridinamine Structure

3-Chloro-4-pyri...

CAS#:19798-77-7

Literature: Nishiwaki, Nagatoshi; Azuma, Mayumi; Tamura, Mina; Hori, Kazushige; Tohda, Yasuo; Ariga, Masahiro Chemical Communications, 2002 , # 18 p. 2170 - 2171

~96%

3-Chloro-4-pyridinamine Structure

3-Chloro-4-pyri...

CAS#:19798-77-7

Literature: Malinowski, Marek Bulletin des Societes Chimiques Belges, 1988 , vol. 97, # 1 p. 51 - 54

~%

3-Chloro-4-pyridinamine Structure

3-Chloro-4-pyri...

CAS#:19798-77-7

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 69, p. 673,690

~%

3-Chloro-4-pyridinamine Structure

3-Chloro-4-pyri...

CAS#:19798-77-7

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. 330, # 1 p. 154 - 158

~%

3-Chloro-4-pyridinamine Structure

3-Chloro-4-pyri...

CAS#:19798-77-7

Literature: Recueil des Travaux Chimiques des Pays-Bas, , vol. 69, p. 673,690

 Customs

HS Code 2933399090
Summary 2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

4-Amino-3-chloropyridine
3-Chloro-pyridin-4-ylamine
3-Chloro-4-pyridinamine
4-Pyridinamine, 3-chloro-
4-Pyridinamine,3-chloro
3-chloro-4-pyridinylamine
3-chloro-4-pyridylamine
3-Chloropyridin-4-ylamine
amino-4 chloro-3 pyridine
3-Chloro-4-aminopyridine
3-chloropyridin-4-amine
3-Chloro-4-pyridinamin
MFCD03984473
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