Kaempferol 3-O-beta-sophoroside

Modify Date: 2024-01-02 13:29:59

Kaempferol 3-O-beta-sophoroside structure	Common Name	Kaempferol 3-O-beta-sophoroside
	CAS Number	19895-95-5	Molecular Weight	610.518
	Density	1.8±0.1 g/cm3	Boiling Point	995.0±65.0 °C at 760 mmHg
	Molecular Formula	C₂₇H₃₀O₁₆	Melting Point	194-198℃
	MSDS	N/A	Flash Point	329.3±27.8 °C

Use of Kaempferol 3-O-beta-sophoroside

Kaempferol 3-O-sophoroside, a derivative of Kaempferol, is isolated from the leaves of cultivated mountain ginseng (Panax ginseng) with anti-inflammatory effects[1].

Name	kaempferol 3-O-β-D-glucosyl-(1→2)-β-D-glucoside
Synonym	More Synonyms

Description	Kaempferol 3-O-sophoroside, a derivative of Kaempferol, is isolated from the leaves of cultivated mountain ginseng (Panax ginseng) with anti-inflammatory effects[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	Kaempferol 3-O-sophoroside possesses barrier integrity activity, inhibitory activity on cell adhesion and migration to endothelial cells by blocking the activation of NF-κB expression and production of TNF-α, thereby endorsing its usefulness as therapy for vascular inflammatory diseases[1].
References	[1]. Kim TH, et al. Anti-inflammatory effects of kaempferol-3-O-sophoroside in human endothelial cells. Inflamm Res. 2012 Mar;61(3):217-24.

Density	1.8±0.1 g/cm3
Boiling Point	995.0±65.0 °C at 760 mmHg
Melting Point	194-198℃
Molecular Formula	C₂₇H₃₀O₁₆
Molecular Weight	610.518
Flash Point	329.3±27.8 °C
Exact Mass	610.153381
PSA	269.43000
LogP	-0.58
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.764

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DJ3068000

CHEMICAL NAME :: 4H-1-Benzopyran-4-one, 3-((2-O-beta-D-glucopyranosyl-beta-diglucopyranosyl)o xy)-5,7- dihydroxy-2-(4-hydroxyphenyl)-

CAS REGISTRY NUMBER :: 19895-95-5

LAST UPDATED :: 199206

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C27-H30-O16

MOLECULAR WEIGHT :: 610.57

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 29,73,1990

Hazard Codes	Xi

N/A

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~49%

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3-O-β-sophorosy...

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Precursor 1
CAS#:87863-90-9 3-O-β-sophorosy...
DownStream 1
CAS#:520-18-3 Kaempferol

5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

Kaempferol-3-sophoroside

4H-1-Benzopyran-4-one, 3-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-

Kaempferol 3-O-sophoroside

Sophoraflavonoloside

K3S

3-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one

kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside