MMSET-IN-1

Modify Date: 2024-04-06 10:17:21

MMSET-IN-1 Structure
MMSET-IN-1 structure
Common Name MMSET-IN-1
CAS Number 1998139-29-9 Molecular Weight 423.47
Density N/A Boiling Point N/A
Molecular Formula C18H29N7O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MMSET-IN-1


MMSET-IN-1 is a multiple myeloma SET domain (MMSET, aka NSD2/WHSC1) inhibitor against SETD2 and MMSET with IC50s of 0.49 and 3.3 μM, respectively. MMSET-IN-1 has a Kd of 1.6 μM for MMSET[1].

 Names

Name MMSET-IN-1

 MMSET-IN-1 Biological Activity

Description MMSET-IN-1 is a multiple myeloma SET domain (MMSET, aka NSD2/WHSC1) inhibitor against SETD2 and MMSET with IC50s of 0.49 and 3.3 μM, respectively. MMSET-IN-1 has a Kd of 1.6 μM for MMSET[1].
Related Catalog
Target

IC50: 0.49 μM (SETD2), 3.3 μM (MMSET)[1] Kd: 1.6 μM[1]

References

[1]. Tisi D, et al. Structure of the Epigenetic Oncogene MMSET and Inhibition by N-Alkyl Sinefungin Derivatives. ACS Chem Biol. 2016 Nov 18;11(11):3093-3105.

 Chemical & Physical Properties

Molecular Formula C18H29N7O5
Molecular Weight 423.47
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